| Synonym | Smoketree Extract |
| CAS No.: | 528-48-3 |
| Form: | Powder |
| Package size: | 25kg, or as per requested |
| Application: | Innovative bulk ingredients for health and nutritional products |
Fisetin 98% is a high-purity flavonol extracted from smoke tree (Cotinus coggygria) and recognized as one of the most powerful natural senolytic and longevity ingredients. Shanghai FanPharma Co., Ltd., a professional bulk supplier, delivers premium smoke tree derived Fisetin powder (≥98% purity, HPLC) with consistent quality and large-scale supply to global dietary supplement and functional food manufacturers.
Fisetin Powder is also available in 20%, 30%, 50% specification.
Typical Benefits
Cellular Health & Longevity:
- Senolytic Activity: Selectively clears senescent cells by inhibiting anti-apoptotic pathways
- NAD+ Enhancement: Increases NAD+ levels through CD38 inhibition
- Sirtuin Activation: Activates SIRT1 and other sirtuins for epigenetic regulation
Antioxidant & Neuroprotective:
- Potent Antioxidant: Strong free radical scavenging capacity with ORAC value ~27300 μmol TE/100g
- Neuroprotection: Crosses blood-brain barrier to support neuronal health and cognitive function
- Metal Chelation: Binds excess iron and copper ions to reduce oxidative stress
Anti-Inflammatory & Metabolic:
- Inflammatory Modulation: Inhibits NF-κB and COX-2 pathways to reduce inflammation
- Metabolic Support: Improves insulin sensitivity and glucose metabolism
- Cardiovascular Health: Supports endothelial function and vascular health
Cellular Signaling & Protection:
- Pathway Modulation: Activates ERK and Nrf2 pathways for cellular defense
- DNA Protection: Reduces oxidative DNA damage and supports repair mechanisms
- Mitochondrial Support: Enhances mitochondrial biogenesis and function
Typical Application
| Application Category | Common Product Formats |
| Longevity & Senolytic Formulas | Capsules, tablets, “senolytic protocol” stacks |
| Cognitive & Brain Health | Nootropic blends, memory-support capsules |
| Anti-Inflammatory Support | Joint-health and recovery formulas |
| Antioxidant Blends | Daily wellness powders, beauty-from-within |
| Functional Foods (limited) | Fortified gummies, shots (requires encapsulation) |
| Private Label / OEM | High-purity custom blends or micronized Fisetin |
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